The association between the sodium-potassium ratio and ICU mortality in cardiac arrest patients: an analysis of the eICU database - Takeaways - MDSpire

The association between the sodium-potassium ratio and ICU mortality in cardiac arrest patients: an analysis of the eICU database

  • By

  • Yuyuan Wang

  • Xin Yuan

  • Dongxia Wang

  • Mingli Li

  • Ruihua Wang

  • June 5, 2026

  • 0 min

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  • 1

    The study analyzed 4,085 ICU patients post-cardiac arrest to investigate the serum sodium-potassium (Na+/K+) ratio's impact on mortality.

  • 2

    A U-shaped relationship was found between the Na+/K+ ratio and ICU mortality, indicating both low and high ratios are associated with increased risk.

  • 3

    Higher Na+/K+ ratios were linked to reduced ICU mortality, with an adjusted odds ratio of 0.75, suggesting a protective effect.

  • 4

    The prognostic value of the Na+/K+ ratio for ICU mortality was consistent across various patient subgroups, with no significant interactions.

  • 5

    Routine assessment of the serum Na+/K+ ratio may enhance risk stratification and clinical management for cardiac arrest patients.

Original Source(s)

The association between the sodium-potassium ratio and ICU mortality in cardiac arrest patients: an analysis of the eICU database

  • by Yuyuan Wang, Xin Yuan, Dongxia Wang, Mingli Li, Ruihua Wang

  • June 5, 2026

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