Global Patterns and Trends in Female Infertility Linked to Sexually Transmitted Infections from 1990 to 2021 - Takeaways - MDSpire

Global Patterns and Trends in Female Infertility Linked to Sexually Transmitted Infections from 1990 to 2021

  • By

  • Tianyu Li

  • Siyu Long

  • Zhishan Ye

  • Zhichen Tang

  • Yaping Song

  • Min Su

  • Bin Zhou

  • Yanyun Wang

  • Lin Zhang

  • February 4, 2026

  • 0 min

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  • 1

    Infertility affects 8%-12% of reproductive-aged individuals globally, equating to 50–80 million couples facing fertility challenges.

  • 2

    Female factors contribute to 40%-50% of infertility cases, highlighting the need to understand female-specific contributors.

  • 3

    Sexually transmitted infections (STIs) are implicated in nearly 30% of female infertility cases, particularly through pelvic inflammatory disease.

  • 4

    The study utilizes the Global Burden of Disease database to evaluate trends and disparities in STIs-related female infertility from 1990 to 2021.

  • 5

    Findings aim to support policymakers in developing targeted interventions to improve global reproductive health outcomes.

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