Preoperative inflammatory and immune-nutritional markers and postoperative pulmonary complications after gastric and colorectal cancer surgery: a systematic review and narrative synthesis - Takeaways - MDSpire

Preoperative inflammatory and immune-nutritional markers and postoperative pulmonary complications after gastric and colorectal cancer surgery: a systematic review and narrative synthesis

  • By

  • Hongyue Zhang

  • Lingyun Zou

  • Hongjuan Fang

  • Hao Wang

  • July 2, 2026

  • 0 min

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  • 1

    Postoperative pulmonary complications (PPCs) are a significant source of morbidity after gastrointestinal cancer surgery.

  • 2

    Fifteen observational studies were included, showing moderate-to-high methodological quality in evaluating preoperative biomarkers.

  • 3

    Adverse preoperative inflammatory and nutritional profiles were generally linked to increased postoperative pulmonary risk.

  • 4

    Key inflammatory markers included the neutrophil-to-lymphocyte ratio and systemic immune-inflammation index.

  • 5

    The literature remains heterogeneous, necessitating standardized studies before biomarkers can be integrated into risk stratification.

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