FibroScan-AST Score vs Liver Stiffness for the Prediction of Liver Events After HCV Cure - Takeaways - MDSpire

FibroScan-AST Score vs Liver Stiffness for the Prediction of Liver Events After HCV Cure

  • By

  • Anaïs Corma-Gómez

  • Diana Corona-Mata

  • Jésica Martín-Carmona

  • María José Galindo

  • Angela Camacho

  • Carmen Martín-Sierra

  • Marina Gallo-Marín

  • Pilar Rincón

  • Ignacio Perez-Valero

  • Margarita Pérez-García

  • Angela Carrasco-Dorado

  • Juan A Pineda

  • Antonio Rivero-Juárez

  • Antonio Rivero

  • Luis M Real

  • Juan Macías

  • on behalf of the GEHEP-011 Study Group

  • April 8, 2025

  • 0 min

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  • 1

    Liver stiffness (LS) is a strong predictor of liver complications in patients with HCV after achieving sustained virological response (SVR).

  • 2

    The FibroScan-AST (FAST) score includes AST and CAP, potentially improving prediction of liver complications compared to LS alone.

  • 3

    In a study of 300 patients, 12% experienced liver complications after SVR, with LS and FAST both independently associated with increased risk.

  • 4

    The area under the receiver operating characteristics curve for LS was 0.83, while for FAST it was 0.80, indicating similar predictive capacities.

  • 5

    FAST does predict liver events post-SVR but does not enhance the predictive ability of LS alone at the time of SVR.

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