Neuroprotection: Retina's Next Frontier? - Takeaways - MDSpire

Neuroprotection: Retina's Next Frontier?

  • By

  • Riad Sherif, MD

  • July 15, 2026

  • 2 min

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  • 1

    Riad Sherif, MD, discussed neuroprotection as a potential next frontier in retinal therapeutics at the 2026 ASRS Meeting.

  • 2

    Oculis is developing privosegtor for the restorative treatment of optic neuritis, an inflammatory condition affecting the optic nerve.

  • 3

    Optic neuritis primarily affects young adults, averaging 32 years old, with about two-thirds of patients being women.

  • 4

    The ongoing PIONEER-1 study is evaluating privosegtor, which previously showed promising results in the ACUITY trial.

  • 5

    Privosegtor improved vision by approximately 18 letters at month 3 and preserved retinal structure by maintaining GCIPL.

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