EDITORIAL: BRAIN CYTOPROTECTION FOR REPERFUSION INJURY AFTER ACUTE ISCHEMIC STROKE - Takeaways - MDSpire

EDITORIAL: BRAIN CYTOPROTECTION FOR REPERFUSION INJURY AFTER ACUTE ISCHEMIC STROKE

  • By

  • Tang, Lujia

  • Zhao, Zilong

  • Zhao, Wenbo

  • IKKA, Léon

  • Liu, Shuling

  • Wei, Ming

  • June 8, 2026

  • 0 min

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  • 1

    Acute ischemic stroke is a leading cause of death and long-term disability globally.

  • 2

    Reperfusion therapies like thrombolysis and thrombectomy improve outcomes but may lead to reperfusion injury.

  • 3

    Reperfusion injury involves excitotoxicity, oxidative stress, and neuroinflammation, limiting recanalization benefits.

  • 4

    Cytoprotection should be central to stroke management, not just an adjunct to reperfusion therapies.

  • 5

    Future stroke management requires integrating early risk stratification and targeted neuroprotection.

Original Source(s)

EDITORIAL: BRAIN CYTOPROTECTION FOR REPERFUSION INJURY AFTER ACUTE ISCHEMIC STROKE

  • by Tang, Lujia , Zhao, Zilong , Zhao, Wenbo , IKKA, Léon , Liu, Shuling , Wei, Ming

  • June 8, 2026

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