Extrapolation of MAP trends predicts hypotension and vasopressor up-titration in the ICU. - Takeaways - MDSpire
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Forecasting MAP Patterns to Anticipate Hypotension and Increased Vasopressor Administration in Intensive Care Units

  • By

  • Iain Edmund Kehoe

  • Jeremy Alanano Pepino

  • Jin-Oh Hahn

  • Mary McAuley

  • Laura Lux

  • Abigail O’Connell

  • Noelle Saillant

  • Haitham S. Alabsi

  • Jarone Lee

  • Andrew Tomas Reisner

  • October 5, 2026

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  • 1

    The median ICU patient experienced hypotension for 119.7 minutes per day, with episodes typically occurring in temporal clusters.

  • 2

    The clinical decision support system (CDSS) predicted 91.7% of vasopressor dose increases during early flickering hypotension.

  • 3

    Every hypotension-cluster was detected by the CDSS, which predicted nearly half of these clusters before they began.

  • 4

    Following positive CDSS predictions, the median cumulative hypotension duration was 26.4 minutes, indicating potential for timely intervention.

  • 5

    Despite visible trends toward hypotension, vasopressors were rarely up-titrated before or during early flickering hypotension.

Original Source(s)

Extrapolation of MAP trends predicts hypotension and vasopressor up-titration in the ICU.

  • by Iain Edmund Kehoe, Jeremy Alanano Pepino, Jin-Oh Hahn, Mary McAuley, Laura Lux, Abigail O’Connell, Noelle Saillant, Haitham S. Alabsi, Jarone Lee, Andrew Tomas Reisner

  • October 5, 2026

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