Bladder sarcoma treated with radical cystectomy and adjuvant epirubicin and ifosfamide chemotherapy: a case report - Takeaways - MDSpire

Bladder sarcoma treated with radical cystectomy and adjuvant epirubicin and ifosfamide chemotherapy: a case report

  • By

  • Jiaxin Liu

  • Hui Han

  • Shuangping Lu

  • Siming Chen

  • Yuchen Jiang

  • Zhu Wang

  • Xuebing Han

  • May 12, 2026

  • 0 min

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  • 1

    Bladder sarcoma is a rare tumor, comprising approximately 0.3% of bladder tumors, complicating preoperative diagnosis due to nonspecific symptoms.

  • 2

    A 53-year-old male patient with painless gross hematuria was diagnosed with a small round cell undifferentiated sarcoma after radical cystectomy.

  • 3

    The patient underwent laparoscopic radical cystectomy with pelvic lymph node dissection and received six cycles of adjuvant chemotherapy with epirubicin and ifosfamide.

  • 4

    At the 12-month follow-up, the patient showed no evidence of tumor recurrence or distant metastasis, indicating short-term efficacy of the treatment.

  • 5

    This case highlights the need for further research on standardized treatment protocols for bladder sarcoma due to its rarity and aggressive nature.

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