Validation of a web-based clinical tool for predicting the risk of bronchopulmonary dysplasia in extremely preterm infants: a retrospective cohort study - Takeaways - MDSpire

Assessment of an Online Clinical Tool for Estimating Bronchopulmonary Dysplasia Risk in Extremely Preterm Infants: A Retrospective Cohort Analysis

  • By

  • Alaa Abuzaid

  • Shadi Noaman Garrada

  • Hebah Salem Abdullah Alsaihati

  • Zainab Alali

  • Fatimah Arif Alabbad

  • Jemila James

  • July 20, 2026

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  • 1

    The study evaluates the NICHD BPD Outcome Estimator (2022) for predicting bronchopulmonary dysplasia in extremely preterm infants.

  • 2

    A total of 501–1250 g neonates born between 23+0 and 28+6 weeks gestational age were included in this retrospective cohort study.

  • 3

    The AUC values for predicting the composite outcome of death or grade 2-3 BPD were 0.71 on postnatal day 7 and 0.76 on day 14.

  • 4

    The estimator demonstrated moderate accuracy, indicating limited clinical utility for predicting BPD outcomes at 36 weeks PMA.

  • 5

    The findings emphasize the need for cautious interpretation and integration of clinical judgment when using prediction models.

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