Psoas Major muscle area as a prognostic marker in peripheral arterial disease: a systematic review and meta-analysis - Takeaways - MDSpire

Psoas Major muscle area as a prognostic marker in peripheral arterial disease: a systematic review and meta-analysis

  • By

  • João Fernandes-Carvalho

  • João Braga-Simões

  • Daniela Santos-Silva

  • Vítor Sá-Martins

  • José Paulo Andrade

  • Hugo Ribeiro

  • João Rocha-Neves

  • July 15, 2026

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  • 1

    This systematic review evaluated the prognostic value of psoas major muscle area in patients with peripheral arterial disease undergoing revascularization.

  • 2

    Seven retrospective cohort studies involving 2,290 patients were included, assessing the association between psoas major area and mortality.

  • 3

    Reduced psoas major muscle area was significantly associated with increased 1-year mortality (RR = 2.37; 95% CI 1.51–3.73; p < 0.001).

  • 4

    The analysis of 1-month mortality suggested a possible increase among sarcopenic patients, but the association was not statistically significant.

  • 5

    The study highlights the need for standardized definitions and prospective studies to clarify the role of psoas morphometry in clinical practice.

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