Association of the triglyceride-glucose index with the severity and short-term prognosis of Guillain-Barré syndrome

1

The triglyceride-glucose (TyG) index is an independent risk factor for severe Guillain-Barré syndrome (GBS) with an odds ratio of 2.77.
2

Albumin levels and the Medical Research Council (MRC) sum score are protective factors against severe GBS.
3

The TyG index is also linked to poor short-term prognosis in GBS patients, with an odds ratio of 1.85.
4

Combining the TyG index with conventional clinical markers improves prediction accuracy for severe GBS and short-term outcomes.
5

Elevated TyG index levels may help clinicians identify high-risk GBS patients for personalized treatment approaches.

Frontiers In Immunology

by Lijuan Wang, Xiang Li, Zikai Zhou, Yuxi Tian, Siwen Li, Wencan Jiang, Kelin Chen, Yuxin Chen, Jie Liu, Guanghui Zheng, Xin gao Wang, Guojun Zhang
June 8, 2026

1