Association between the HALP score and survival of patients with esophageal or gastro-esophageal junction cancer: a meta-analysis - Takeaways - MDSpire

Association between the HALP score and survival of patients with esophageal or gastro-esophageal junction cancer: a meta-analysis

  • By

  • Wu Wang

  • Junhai Chen

  • Tianbao Yang

  • June 23, 2026

  • 0 min

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  • 1

    The HALP score combines hemoglobin, albumin, lymphocyte, and platelet levels, indicating nutritional and inflammatory conditions.

  • 2

    A meta-analysis of ten cohort studies with 1,953 patients assessed the relationship between HALP scores and survival outcomes in esophageal cancer.

  • 3

    Patients with low HALP scores showed significantly inferior overall survival compared to those with high HALP scores (HR: 1.74, 95% CI: 1.53-1.98).

  • 4

    Low HALP scores were also associated with diminished progression-free survival in five studies (HR: 1.82, 95% CI: 1.40-2.37).

  • 5

    The findings suggest that reduced baseline HALP scores correlate with poorer overall and progression-free survival in esophageal and gastro-esophageal junction cancer.

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