Nonlinear association between serum insulin, visceral fat area, and kidney function in female with type 2 diabetes: a retrospective study - Takeaways - MDSpire

Nonlinear association between serum insulin, visceral fat area, and kidney function in female with type 2 diabetes: a retrospective study

  • By

  • Yuqin Gan

  • Mengjie Chen

  • Zhitao Xiao

  • Bo Li

  • Yu Gao

  • Kaili Dai

  • June 1, 2026

  • 0 min

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  • 1

    This study analyzed nonlinear relationships between fasting insulin levels, visceral fat area, and renal function in women with type 2 diabetes.

  • 2

    A total of 595 female patients with type 2 diabetes were included after excluding those with incomplete data.

  • 3

    Fasting insulin levels above 70.28 pmol/L negatively correlated with estimated glomerular filtration rate, indicating renal function impairment.

  • 4

    Visceral fat area above 73.6 cm² was negatively correlated with renal function, while lower values showed a positive correlation.

  • 5

    The findings suggest critical thresholds for fasting insulin and visceral fat area that may aid in risk stratification for renal function in diabetic women.

Original Source(s)

Nonlinear association between serum insulin, visceral fat area, and kidney function in female with type 2 diabetes: a retrospective study

  • by Yuqin Gan, Mengjie Chen, Zhitao Xiao, Bo Li, Yu Gao, Kaili Dai

  • June 1, 2026

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