Regional Brain Structure Alterations in Diabetes but Not Prediabetes - Takeaways - MDSpire

Regional Brain Structure Alterations in Diabetes but Not Prediabetes

  • By

  • Liangqi Wang

  • Huandong Lin

  • Zehua Zhao

  • Lingyan Chen

  • Li Wu

  • Ting Liu

  • Jing Li

  • Chu-Chung Huang

  • Chun-Yi Zac Lo

  • Xin Gao

  • April 30, 2025

  • 0 min

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  • 1

    Diabetes significantly alters brain structures, particularly gray matter volume, affecting areas related to movement and coordination.

  • 2

    Cognitive decline, as measured by the Montreal Cognitive Assessment, correlates with brain changes in diabetes but not in prediabetes.

  • 3

    White matter hyperintensity is significantly higher in individuals with diabetes compared to controls, indicating advanced brain changes.

  • 4

    Glycemic levels are positively correlated with white matter hyperintensity across multiple brain tracts in diabetes.

  • 5

    The study challenges the notion that brain changes begin in prediabetes, emphasizing the need for diabetes prevention.

Original Source(s)

Regional Brain Structure Alterations in Diabetes but Not Prediabetes

  • by Liangqi Wang, Huandong Lin, Zehua Zhao, Lingyan Chen, Li Wu, Ting Liu, Jing Li, Chu-Chung Huang, Chun-Yi Zac Lo, Xin Gao

  • April 30, 2025

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