Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study - Takeaways - MDSpire

Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study

  • By

  • Rongling Zhang

  • Xiao Shang

  • Chunlei Wang

  • Hong Zhou

  • Nana Liu

  • Xiaochen Shen

  • Zeyi Wang

  • Jiuyang Xu

  • Dingrong Zhong

  • Hui Li

  • Bin Cao

  • December 26, 2025

  • 0 min

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  • 1

    Human rhinovirus (HRV) was detected in 4.6% of hospitalized adults with lower respiratory tract infections (LRTIs) during the study period.

  • 2

    Co-infection with other pathogens occurred in 49.0% of HRV-positive patients, predominantly with bacteria and other viruses.

  • 3

    Among HRV-positive patients, 224 cases developed pneumonia, but only 34 (7.8%) were classified as simple viral pneumonia.

  • 4

    Independent predictors of simple rhinovirus pneumonia included male gender, fever, and cough, highlighting specific risk factors.

  • 5

    Immunofluorescence staining confirmed HRV infection in lower respiratory tract cells, providing histological evidence of its pathogenic role.

Original Source(s)

Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study

  • by Rongling Zhang, Xiao Shang, Chunlei Wang, Hong Zhou, Nana Liu, Xiaochen Shen, Zeyi Wang, Jiuyang Xu, Dingrong Zhong, Hui Li, Bin Cao

  • December 26, 2025

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