Association Between Systemic Immune-Inflammation Index and Postoperative Optical Quality in the Early Recovery Phase After Cataract Surgery: A Retrospective Study

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Higher preoperative systemic immune-inflammation index (SII) correlates with lower internal modulation transfer function (MTF) average height post-cataract surgery.
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The study analyzed 110 eyes from 110 patients who underwent phacoemulsification with monofocal intraocular lens implantation.
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Significant associations were found between higher log2-SII and lower internal MTF average height at 1 week and 1 month post-surgery.
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Exploratory analyses indicated that the low-SII group had better optical quality metrics, including Strehl ratio and lower higher-order aberrations.
5

Despite similar visual acuity outcomes, systemic inflammatory status may influence early optical recovery variability following cataract surgery.

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