Therapeutic potential of stem cells in addressing female infertility: recent progress and prospective developments - Takeaways - MDSpire

Therapeutic potential of stem cells in addressing female infertility: recent progress and prospective developments

  • By

  • Yuyi Wu

  • Siying Chen

  • Ruotong Hao

  • Ruipeng Wang

  • Liandi Mai

  • July 6, 2026

  • 0 min

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  • 1

    Female infertility affects 10–15% of women of reproductive age and is often due to ovarian insufficiency and endometrial damage.

  • 2

    Stem cell therapies show promise in improving ovarian function and endometrial receptivity through mechanisms like paracrine signaling and immunomodulation.

  • 3

    Mesenchymal stem cells (MSCs) are the most researched type for infertility, with sources including bone marrow and umbilical cord.

  • 4

    Induced pluripotent stem cells (iPSCs) can differentiate into various cell types and have potential for artificial gametogenesis.

  • 5

    Current clinical research favors MSCs due to their higher safety profiles and fewer ethical concerns compared to embryonic stem cells.

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