Comparative effects of structured exercise protocols on depression and anxiety symptoms: a network meta-analysis - Takeaways - MDSpire

Comparative effects of structured exercise protocols on depression and anxiety symptoms: a network meta-analysis

  • By

  • Zhiyuan Zhang

  • Fengyun Li

  • Can Han

  • Wenkun Song

  • Sifan Pu

  • June 8, 2026

  • 0 min

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  • 1

    The study systematically compared eight structured exercise modalities for their effects on depressive and anxiety symptoms in adults.

  • 2

    A total of 22 studies with 1,830 participants were included, demonstrating significant improvements in depressive and anxiety symptoms through exercise.

  • 3

    Yoga ranked highest for improving both depression and anxiety symptoms, followed closely by moderate-intensity continuous training and high-intensity interval training.

  • 4

    Subgroup analyses indicated larger effect sizes in the elderly, but no significant moderating effects were found based on intervention duration or age.

  • 5

    The findings support the use of various exercise modalities in clinical practice, emphasizing individualized regimens based on patient preferences and symptom profiles.

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