Evaluation of antibiotic consumption and resistance patterns among neonates: a 10-year retrospective study - Takeaways - MDSpire

Evaluation of antibiotic consumption and resistance patterns among neonates: a 10-year retrospective study

  • By

  • Wiona Denita Moras

  • Raushan Kumar Chaudhary

  • Soumya Patil

  • Seema Pavaman Sindgikar

  • Deepthi Avvaru

  • Uday Venkat Mateti

  • May 12, 2026

  • 0 min

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  • 1

    A retrospective study over 10 years evaluated antibiotic consumption and resistance patterns among 447 neonates in a tertiary care hospital.

  • 2

    Aminoglycosides, penicillin, and cephalosporins were the most commonly prescribed antibiotics, with significant resistance observed.

  • 3

    Coagulase-negative staphylococci, Klebsiella pneumoniae, and Staphylococcus aureus were the top three microorganisms identified.

  • 4

    Sixteen of the 21 identified isolates were multidrug resistant, highlighting a critical need for antimicrobial stewardship in neonatal care.

  • 5

    The study found a significant correlation between antibiotic consumption and resistance patterns, particularly for penicillin and aminoglycosides.

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