Gender-Based Variations in Long-Term Overall and Cause-Specific Mortality Among Cirrhosis Patients

1

Cirrhosis accounts for over 1 million deaths annually, with its prevalence projected to rise by more than 50% by 2030.
2

Biological sex influences the causes and clinical severity of cirrhosis, with males more affected by viral hepatitis and females by cholestatic or autoimmune causes.
3

Current evidence on sex disparities in cirrhosis mortality is limited, with some studies suggesting a female survival advantage and others indicating disadvantages.
4

This study conducted a population-based evaluation of sex-related differences in long-term overall and cause-specific mortality among cirrhosis patients.
5

The study utilized a retrospective cohort design, analyzing data from hospitalized cirrhosis patients in California from 2005 to 2019.

1