Combined prognostic value of lipoprotein(a) and an integrated inflammatory-lipid index in patients with acute coronary syndrome and type 2 diabetes mellitus - Takeaways - MDSpire

Combined prognostic value of lipoprotein(a) and an integrated inflammatory-lipid index in patients with acute coronary syndrome and type 2 diabetes mellitus

  • By

  • Tingting Li

  • Hongliang Cong

  • Lin Wang

  • Wei Ruo

  • Wenyu Li

  • June 2, 2026

  • 0 min

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  • 1

    Lipoprotein(a) and a novel Inflammatory-Lipid Index are independent predictors of major adverse cardiovascular events in ACS patients with type 2 diabetes.

  • 2

    The study analyzed 1,910 patients over a median follow-up of 5.5 years, confirming the prognostic value of Lp(a) and the Inflammatory-Lipid Index.

  • 3

    Patients with high levels of both Lp(a) and the Inflammatory-Lipid Index had a MACE incidence of 57.7%, indicating a significantly elevated risk.

  • 4

    Adding Lp(a) and the Inflammatory-Lipid Index to traditional risk models improved predictive performance and reclassification for cardiovascular risk.

  • 5

    The study introduces a combined assessment approach that enhances risk stratification for diabetic ACS patients beyond conventional factors.

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