A comparative study of mirabegron versus doxazosin in improving ureteral stent-related dysfunction - Takeaways - MDSpire

A comparative study of mirabegron versus doxazosin in improving ureteral stent-related dysfunction

  • By

  • Bo Tao

  • Enyan Jiang

  • Yuan Zhao

  • Zhangxiao Xu

  • Juan Yang

  • Lijun Wang

  • May 13, 2025

  • 0 min

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  • 1

    Ureteral stents are commonly used in urological procedures but can cause significant stent-related symptoms (SRS) affecting quality of life.

  • 2

    Doxazosin and mirabegron are medications used to alleviate SRS, with doxazosin being an alpha-blocker and mirabegron a β3-adrenergic receptor agonist.

  • 3

    This study aimed to compare the efficacy and side effects of mirabegron and doxazosin in improving ureteral stent symptoms, particularly sexual dysfunction.

  • 4

    The study was a double-blind, randomized trial conducted at Anning First People's Hospital, involving participants with ureteral stones.

  • 5

    Primary outcomes included pain during intercourse and sexual dissatisfaction, assessed using the Ureteral Stent Symptoms Questionnaire (USSQ).

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