Hormonal Influence on Corneal Changes in Keratoconus: A Comprehensive Analysis of Tomographic and Biomechanical Differences by Gender, Age, and Menstrual Cycle - Takeaways - MDSpire

Hormonal Influence on Corneal Changes in Keratoconus: A Comprehensive Analysis of Tomographic and Biomechanical Differences by Gender, Age, and Menstrual Cycle

  • By

  • Xiaorui Zhao

  • Ruiyu Zhang

  • Tong Sun

  • Yifei Yuan

  • Yu Zhang

  • Yueguo Chen

  • February 11, 2026

  • 0 min

Share

  • 1

    Keratoconus is a progressive corneal disorder with a prevalence of 0.004%-0.06%, typically stabilizing by the third decade of life.

  • 2

    Males generally experience earlier onset of keratoconus, with a male-to-female ratio ranging from 0.9:1 to 2.5:1.

  • 3

    This study investigates the influence of sex hormones on corneal changes in keratoconus patients, focusing on hormonal profiles and corneal parameters.

  • 4

    Significant differences in testosterone and estradiol levels were observed between keratoconus patients and controls.

  • 5

    The study highlights the need for further research into the hormonal mechanisms affecting keratoconus progression.

Original Source(s)

Hormonal Influence on Corneal Changes in Keratoconus: A Comprehensive Analysis of Tomographic and Biomechanical Differences by Gender, Age, and Menstrual Cycle

  • by Xiaorui Zhao, Ruiyu Zhang, Tong Sun, Yifei Yuan, Yu Zhang, Yueguo Chen

  • February 11, 2026

Related Content

Evaluation of Corneal Thickness Using the New Revo FC Optical Coherence Tomographer Compared to the Pentacam Scheimpflug Imaging System

HPV Linked to Thyroid Eye Disease

Patients with the eye disorder were more likely to have had low-risk HPV before hyperthyroidism diagnosis.

Challenging Refractions

Dr. McKinnis describes what to do when visual acuity alone does not fully capture visual quality.