Atherosclerosis risk in women with polycystic ovarian syndrome: it’s not just the comorbidities - Takeaways - MDSpire

Atherosclerosis risk in women with polycystic ovarian syndrome: it’s not just the comorbidities

  • By

  • Katharine A Bate

  • Gemma A Figtree

  • December 17, 2025

  • 0 min

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  • 1

    Polycystic ovary syndrome (PCOS) affects 10-13% of reproductive-age women and is linked to increased cardiovascular disease risk.

  • 2

    A study found women with PCOS had a 25-year cumulative incidence of acute coronary syndrome and ischaemic stroke of 3.4%, higher than controls at 2.0%.

  • 3

    PCOS was associated with a higher risk of recurrent cardiovascular events, with rates of 65.3% compared to 59.7% in controls during follow-up.

  • 4

    The association between PCOS and cardiovascular outcomes persisted even after adjusting for various comorbidities and medication use.

  • 5

    This study emphasizes the need for further research on cardiovascular risk profiles in women with PCOS, particularly during their reproductive years.

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