Changes in Malondialdehyde, 8-iso-prostaglandin F2α, and Lipid Profiles Among COVID-19 Patients: Findings from South-Western Nigeria - Takeaways - MDSpire

Changes in Malondialdehyde, 8-iso-prostaglandin F2α, and Lipid Profiles Among COVID-19 Patients: Findings from South-Western Nigeria

  • By

  • Maria Onomhaguan Ebesunun

  • Donatus Uchechukwu Ozegbe

  • Promise Chineye Nwaejigh

  • Bose Etaniamhe Orimadegun

  • Obiageri Ihuarulam Okeoma

  • January 20, 2026

  • 0 min

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  • 1

    COVID-19 in Nigeria is associated with oxidative stress and lipid metabolism dysregulation, impacting disease progression and complications.

  • 2

    Malondialdehyde and 8-iso-prostaglandin F2α levels indicate oxidative stress and cellular damage in COVID-19 patients.

  • 3

    Lipid profiles, including total cholesterol and LDL-C, are often lower in severe COVID-19 cases, suggesting a link to disease severity.

  • 4

    Co-infections like malaria exacerbate oxidative stress in COVID-19 patients, highlighting the need for region-specific research.

  • 5

    The study aims to provide insights into metabolic disturbances in COVID-19 among African populations, addressing a significant data gap.

Original Source(s)

Changes in Malondialdehyde, 8-iso-prostaglandin F2α, and Lipid Profiles Among COVID-19 Patients: Findings from South-Western Nigeria

  • by Maria Onomhaguan Ebesunun, Donatus Uchechukwu Ozegbe, Promise Chineye Nwaejigh, Bose Etaniamhe Orimadegun, Obiageri Ihuarulam Okeoma

  • January 20, 2026

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