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1
Cholangiocytes are dynamic cells involved in bile secretion, epithelial repair, immune signaling, and can contribute to chronic diseases.
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2
Cholangiocyte plasticity can lead to maladaptive responses, resulting in chronic inflammation, fibrosis, and carcinogenesis.
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3
Genetic cholangiopathies illustrate how altered biliary development can produce lifelong cholestatic conditions requiring genotype-informed follow-up.
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4
A prognostic nomogram for primary biliary cholangitis integrates clinical factors to predict 5-year survival in treated patients.
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5
Cholangiopathies represent a spectrum of disorders, from immune-mediated diseases to malignancies, necessitating comprehensive diagnostic approaches.
