Insomnia Outcomes May Vary by Measurement Method  - Takeaways - MDSpire

Insomnia Outcomes May Vary by Measurement Method 

  • By

  • Henry Thomas

  • February 12, 2026

  • 3 min

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  • 1

    Standard patient-reported outcome measures may overlook daytime effects of insomnia pharmacotherapy.

  • 2

    A randomized trial showed suvorexant improved insomnia severity but revealed time-of-day effects on fatigue and cognition using smartphone-based EMA.

  • 3

    Participants treated with suvorexant experienced greater morning fatigue and reduced alertness earlier in the day compared to placebo.

  • 4

    EMA demonstrated significant treatment-related differences in daytime symptoms, highlighting its feasibility in older adults.

  • 5

    The study suggests broader EMA adoption could enhance insomnia therapy evaluations and support patient-centered treatment decisions.

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