A connectome-based neural correlate of pediatric ADHD hyperactivity–impulsivity symptoms

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The study involved 44 children with ADHD, utilizing resting-state fMRI data to examine brain networks related to hyperactivity and impulsivity.
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Connectome-based predictive modeling successfully predicted hyperactivity-impulsivity symptoms with significant correlation coefficients from parent and teacher ratings.
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Stronger connectivity between the frontoparietal control network and dorsal attention network was associated with greater symptom severity in ADHD.
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Weaker connectivity was observed between the frontoparietal control network and both the ventral attention network and somatomotor network.
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The findings suggest that whole-brain functional connectivity may serve as a preliminary neuroimaging marker for ADHD symptom severity.

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