Prognostic Implications of Post-Endovascular Therapy Contrast Staining in Basilar Artery Occlusion Stroke - Takeaways - MDSpire

Prognostic Implications of Post-Endovascular Therapy Contrast Staining in Basilar Artery Occlusion Stroke

  • By

  • Natascha Hohmann

  • Matthias P. Fabritius

  • Sijing Gu

  • Daniel Puhr-Westerheide

  • Philipp Lohse

  • Steffen Tiedt

  • Lars Kellert

  • Konstantinos Dimitriadis

  • Sergio Grosu

  • Thomas Liebig

  • Jens Ricke

  • Wolfgang G. Kunz

  • Osman Öcal

  • Paul Reidler

  • April 28, 2026

  • 0 min

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  • 1

    Contrast staining after endovascular therapy for basilar artery occlusion indicates blood-brain barrier disruption and prolonged tissue absorption of contrast media.

  • 2

    In a study of 42 patients, 42.9% exhibited contrast staining, which was associated with significantly worse functional outcomes at 90 days.

  • 3

    Patients with contrast staining had a median modified Rankin scale score of 6, indicating unfavorable outcomes compared to a score of 2 in those without staining.

  • 4

    Multivariable LASSO analysis confirmed a significant association between contrast staining and poor clinical outcomes, surpassing other imaging parameters.

  • 5

    The study highlights the prognostic value of post-interventional contrast staining in predicting outcomes for patients with basilar artery occlusion stroke.

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