High Seroprevalence of Hepatitis E Virus Among Patients With Hepatitis B and Those With Hepatitis of Unknown Etiology in Central Vietnam - Takeaways - MDSpire

High Seroprevalence of Hepatitis E Virus Among Patients With Hepatitis B and Those With Hepatitis of Unknown Etiology in Central Vietnam

  • By

  • Le Chi Cao

  • Tran Thi Tien Xinh

  • Taanvi Gowdar

  • Dang Ngoc Phuoc

  • Nguyen Thi Dung

  • Tran Thi Kim Loan

  • Pham Van Duc

  • Dao Thi Huyen

  • Le Thi Kieu Linh

  • Le Huu Song

  • Thirumalaisamy P Velavan

  • June 26, 2025

  • 0 min

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  • 1

    The study found an anti-HEV IgG seroprevalence of 26% in patients with HBV and 36% in those with hepatitis of unknown etiology in Central Vietnam.

  • 2

    Patients with liver cirrhosis and hepatocellular carcinoma had the highest anti-HEV IgG seroprevalence at 46%, while symptomatic chronic hepatitis B patients had the lowest at 24%.

  • 3

    Only 1 patient (0.1%) tested positive for anti-HEV immunoglobulin M, and no HEV RNA positivity was detected among the study participants.

  • 4

    Biochemical parameters in patients with liver diseases showed no association with anti-HEV seropositivity, indicating limited impact of HEV on liver disease progression.

  • 5

    The findings suggest that HEV is not a common cause of hepatitis in Central Vietnam, despite relatively high seroprevalence among chronic liver disease patients.

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