Longitudinal changes in nutritional status during induction chemotherapy and their association with treatment outcomes in pediatric patients with newly diagnosed acute myeloid leukemia - Takeaways - MDSpire

Longitudinal changes in nutritional status during induction chemotherapy and their association with treatment outcomes in pediatric patients with newly diagnosed acute myeloid leukemia

  • By

  • Chun-lei Liu

  • Fan-ling Yan

  • Xiao-ling Li

  • June 1, 2026

  • 0 min

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  • 1

    This study analyzed nutritional changes in pediatric AML patients during induction chemotherapy and their impact on treatment outcomes.

  • 2

    Weight Z-score, BMI Z-score, and serum albumin were monitored at four time points, revealing a decline followed by recovery.

  • 3

    Severe weight Z-score decline correlated with lower remission rates, higher treatment-related mortality, and increased complications.

  • 4

    Multivariate analysis identified significant predictors of poor outcomes, including weight Z-score decline greater than 1.0.

  • 5

    Findings support early nutritional intervention based on dynamic monitoring of nutritional status during chemotherapy.

Original Source(s)

Longitudinal changes in nutritional status during induction chemotherapy and their association with treatment outcomes in pediatric patients with newly diagnosed acute myeloid leukemia

  • by Chun-lei Liu, Fan-ling Yan, Xiao-ling Li

  • June 1, 2026

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