‘It works in practice, but does it work in theory?’ An important addition to the body of real-world evidence supporting carotid endarterectomy - Takeaways - MDSpire

‘It works in practice, but does it work in theory?’ An important addition to the body of real-world evidence supporting carotid endarterectomy

  • By

  • Kirthi S Bellamkonda

  • David H Stone

  • Jesse A Columbo

  • July 6, 2026

  • 0 min

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  • 1

    Carotid artery stenosis is a major cause of stroke, with CEA, CAS, and TCAR as primary revascularization procedures to reduce long-term stroke risk.

  • 2

    A study of nearly 150,000 patients in France found that CEA had a lower 30-day stroke or death risk compared to CAS for both asymptomatic and symptomatic patients.

  • 3

    The study reported 98% postoperative medical therapy compliance, indicating that high adherence rates can be achieved in real-world practice.

  • 4

    Observational studies like this one highlight potential disparities in outcomes compared to randomized trials, raising questions about generalizability.

  • 5

    The findings suggest that CEA may offer superior stroke outcomes compared to CAS, contributing to ongoing debates about optimal treatment for carotid disease.

Original Source(s)

‘It works in practice, but does it work in theory?’ An important addition to the body of real-world evidence supporting carotid endarterectomy

  • by Kirthi S Bellamkonda, David H Stone, Jesse A Columbo

  • July 6, 2026

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