A meta-analysis of influencing factors of non-suicidal self-injury behavior in adolescents with depression - Takeaways - MDSpire

A meta-analysis of influencing factors of non-suicidal self-injury behavior in adolescents with depression

  • By

  • Yanfei Zheng

  • Xudong Zhao

  • Leiwen Tang

  • July 13, 2026

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  • 1

    This systematic review and meta-analysis analyzed factors influencing non-suicidal self-injury (NSSI) in adolescents with depression.

  • 2

    The study included 11 observational studies with a total of 2,245 participants, comparing adolescents with and without NSSI.

  • 3

    Adolescents with NSSI exhibited significantly higher scores in interpersonal problems, negative emotions, and childhood trauma compared to controls.

  • 4

    The meta-analysis revealed significant differences in emotional abuse, physical abuse, and neglect between adolescents with and without NSSI.

  • 5

    Findings suggest that psychosocial and emotional factors play important roles in the occurrence of NSSI behaviors in depressed adolescents.

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