Correlation between Staphylococcus aureus colonization and disease severity in atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials - Takeaways - MDSpire

Correlation between Staphylococcus aureus colonization and disease severity in atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials

  • By

  • Ruyi Jin

  • Mingyue Wang

  • Jincheng Ke

  • Xinghua Gao

  • Li Zhang

  • May 7, 2026

  • 0 min

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  • 1

    A systematic review and meta-analysis evaluated the correlation between Staphylococcus aureus colonization and atopic dermatitis severity.

  • 2

    Seven randomized controlled trials with 929 subjects were included, revealing a moderate positive association (r = 0.42, 95% CI: 0.31–0.52).

  • 3

    The analysis showed moderate heterogeneity among studies (I² = 38%, P = 0.14), but sensitivity and subgroup analyses supported the primary results.

  • 4

    S. aureus colonization is linked to increased severity of atopic dermatitis, but this does not imply a direct causal relationship.

  • 5

    The study emphasizes the need for standardized methodologies in future research to better understand the S. aureus and AD severity connection.

Original Source(s)

Correlation between Staphylococcus aureus colonization and disease severity in atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials

  • by Ruyi Jin, Mingyue Wang, Jincheng Ke, Xinghua Gao, Li Zhang

  • May 7, 2026

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