Prognostic Implications of Widespread FDG Uptake in Spleen and/or Bone Marrow Linked to Reticuloendothelial System Activation in Patients with Lymphoma - Takeaways - MDSpire

Prognostic Implications of Widespread FDG Uptake in Spleen and/or Bone Marrow Linked to Reticuloendothelial System Activation in Patients with Lymphoma

  • By

  • Yuru Song

  • Jiaqi Sun

  • Jing Jiang

  • Ningjun Xu

  • Qian Zhao

  • January 17, 2026

  • 0 min

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  • 1

    Lymphoma is a malignant disorder with increasing global incidence, characterized by aggressive behavior and multi-organ involvement.

  • 2

    Functional imaging, particularly ¹⁸F-FDG PET/CT, is crucial for diagnosing lymphoma and assessing treatment response.

  • 3

    Diffuse FDG uptake in the spleen and bone marrow may indicate systemic inflammation and has unclear prognostic significance in lymphoma.

  • 4

    The study aims to evaluate the prognostic value of diffuse FDG uptake in lymphoma patients and its correlation with inflammatory markers.

  • 5

    Integrating PET/CT metrics with inflammatory parameters may enhance prognostic stratification and guide individualized treatment strategies.

Original Source(s)

Prognostic Implications of Widespread FDG Uptake in Spleen and/or Bone Marrow Linked to Reticuloendothelial System Activation in Patients with Lymphoma

  • by Yuru Song, Jiaqi Sun, Jing Jiang, Ningjun Xu, Qian Zhao

  • January 17, 2026

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