Editorial: Advancement of chemotherapy in breast cancer: predictive markers, resistance mechanism and therapeutic strategies - Takeaways - MDSpire

Editorial: Advancement of chemotherapy in breast cancer: predictive markers, resistance mechanism and therapeutic strategies

  • By

  • Richard Beatson

  • Jinhai Deng

  • Teng Pan

  • Zhendong Shi

  • Ming Zhao

  • July 3, 2026

  • 0 min

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  • 1

    The editorial summarizes advancements in breast cancer chemotherapy, focusing on predictive markers, resistance mechanisms, and therapeutic strategies.

  • 2

    Dewidar et al. found that pentoxifylline significantly reduces chemotherapy-induced neuropathy and mucositis in breast cancer patients.

  • 3

    Iqbal et al. reported that trimetazidine effectively decreases paclitaxel-induced peripheral neuropathy in non-metastatic breast cancer patients.

  • 4

    Li et al. proposed the Selective Lipid Metabolism Therapy Benefit Hypothesis, emphasizing the need for predictive biomarkers in breast cancer treatment.

  • 5

    Liao et al. developed a predictive nomogram for triple-negative breast cancer, demonstrating high accuracy for pathological complete response and survival outcomes.

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