Association of respiratory viral detection with complex febrile seizures and hospitalisation in children after the COVID-19 pandemic: a retrospective observational study - Takeaways - MDSpire
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Impact of Respiratory Virus Detection on Complex Febrile Seizures and Hospitalization Rates in Children Following the COVID-19 Pandemic: A Retrospective Observational Analysis

  • By

  • Ho-Young Song

  • So-Hyun Paek

  • Jae-Hyun Kwon

  • Soo Hyun Park

  • Min-Jung Kim

  • Young-Hoon Byun

  • Jin Hee Kim

  • Sung-Ha Kim

  • June 10, 2026

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  • 1

    The study analyzed 558 children aged 6–60 months with febrile seizures who underwent multiplex respiratory virus RT-PCR testing.

  • 2

    Seventeen percent of the children had complex febrile seizures, with parainfluenza and seasonal coronaviruses linked to lower odds of CFS.

  • 3

    Parainfluenza virus and respiratory syncytial virus were associated with reduced odds of hospitalization in children with febrile seizures.

  • 4

    Viral co-detection occurred in 47.8% of cases, with each additional virus correlating with lower odds of CFS and hospitalization.

  • 5

    The findings suggest cautious interpretation of multiplex RT-PCR results, emphasizing the need for further research on virus interactions.

Original Source(s)

Association of respiratory viral detection with complex febrile seizures and hospitalisation in children after the COVID-19 pandemic: a retrospective observational study

  • by Ho-Young Song, So-Hyun Paek, Jae-Hyun Kwon, Soo Hyun Park, Min-Jung Kim, Young-Hoon Byun, Jin Hee Kim, Sung-Ha Kim

  • June 10, 2026

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