Potential role of maintaining physiological testosterone levels in improving glucose metabolism among normal-weight Japanese women: a pilot exploratory study - Takeaways - MDSpire

Potential role of maintaining physiological testosterone levels in improving glucose metabolism among normal-weight Japanese women: a pilot exploratory study

  • By

  • Takahiro Tsutsumi

  • Saki Komai

  • Asako Miyazaki

  • Kyoichiro Tsuchiya

  • July 6, 2026

  • 0 min

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  • 1

    This study investigates the relationship between serum total testosterone levels and glucose metabolism in normal-weight Japanese women.

  • 2

    Significant inverse correlations were found between total testosterone levels and HbA1c, fasting glucose, and HOMA-IR.

  • 3

    The inverse associations with HbA1c and fasting glucose remained significant after adjusting for BMI and lifestyle factors.

  • 4

    The association between total testosterone and HOMA-IR remained significant after adjusting for age and menopausal status.

  • 5

    The findings suggest that maintaining physiological testosterone levels may be important for glucose metabolism in normal-weight women.

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