What are the beneficial treatment strategies in maintaining T lymphocyte subsets after cancer surgery? A systematic review and network meta-analysis - Takeaways - MDSpire

What are the beneficial treatment strategies in maintaining T lymphocyte subsets after cancer surgery? A systematic review and network meta-analysis

  • By

  • Ziang Xu

  • Yikun Zhang

  • Yanyu Huo

  • Zihua Xu

  • Chenze Wang

  • Chengkang Wang

  • Yingshi Zhang

  • Qingchun Zhao

  • July 14, 2026

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  • 1

    The study systematically evaluates various treatment strategies to maintain T lymphocyte subsets in cancer surgery patients.

  • 2

    Eighty-two randomized controlled trials were included in the analysis to assess the impact on immune parameters.

  • 3

    Immune-enhanced enteral nutrition combined with neoadjuvant chemotherapy ranked highest for improving CD4+ counts.

  • 4

    Other effective strategies included targeted therapy, the Enhanced Recovery After Surgery protocol, and specific anesthesia techniques.

  • 5

    The study emphasizes the importance of multimodal strategies for preserving postoperative T lymphocyte homeostasis.

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