Primary malignant solitary fibrous tumor of the neck in an HIV-positive patient: a case report - Takeaways - MDSpire
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Malignant Solitary Fibrous Tumor in the Cervical Area of an HIV-Positive Individual: A Case Study

  • By

  • Jing Liu

  • Siying Zhu

  • Cheng-xi Wang

  • Yuejuan Zhao

  • August 19, 2026

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  • 1

    A 54-year-old HIV-positive male presented with a malignant solitary fibrous tumor in the cervical region, exhibiting aggressive bone destruction and lung metastasis.

  • 2

    The tumor measured approximately 10.0 cm x 8.0 cm x 4.0 cm and was associated with radiating pain in the right upper limb over a 5-month period.

  • 3

    Initial biopsy suggested a mesenchymal malignant tumor, potentially a BCOR-altered sarcoma, complicating the diagnostic process.

  • 4

    The patient underwent two cycles of neoadjuvant chemotherapy followed by surgical resection, leading to a definitive diagnosis of malignant solitary fibrous tumor.

  • 5

    Histopathological analysis confirmed the diagnosis, highlighting the importance of thorough immunohistochemical profiling in distinguishing rare sarcomas.

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