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1
Ischemic stroke is a leading cause of death and disability, with significant global economic impacts exceeding US$891 billion annually.
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2
Acupuncture is widely used in stroke rehabilitation, showing potential benefits in dysphagia, depressive symptoms, and cognitive impairment.
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3
The clinical efficacy of acupuncture remains uncertain due to varying outcomes, study designs, and unresolved methodological issues.
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4
Emerging research highlights the role of metabolic reprogramming in ischemic stroke, linking acupuncture to mitochondrial function and oxidative stress.
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5
Future studies should adopt biomarker-anchored, phenotype-specific designs to clarify acupuncture's role in ischemic stroke recovery.