Can MRI Predict Perforator Stroke Progression?
Investigators evaluate multisequence imaging for its ability to identify patients at risk for neurologic progression.
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By
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Kathryn Wighton
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February 24, 2026
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A radiomics model using multiparameter MRI can predict neurologic deterioration in subacute ischemic perforator artery infarction.
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The model achieved an area under the curve of 0.844 in the training cohort and 0.824 in the validation cohort.
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The study included 188 patients with single-lesion subacute ischemic perforator artery cerebral infarction.
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Combined radiomic features from multiple MRI sequences outperformed single-sequence models in predicting progression.
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The study faced limitations including modest sample size, lack of external validation, and retrospective design.