Interstitial Photodynamic Therapy (PDT) for the Treatment of Patients with Locally Advanced or Recurrent Head and Neck Cancer - Takeaways - MDSpire

Interstitial Photodynamic Therapy (PDT) for the Treatment of Patients with Locally Advanced or Recurrent Head and Neck Cancer

An NCI/NIH funded Phase 1/2 clinical study (NCT03727061) will evaluate the safety and efficacy of adjuvant Photofrin® mediated I-PDT in patients with locally advanced or recurrent HNC who failed to respond to standard therapy and are not amenable to standard curative treatment.

  • August 5, 2019

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  • 1

    Porfimer sodium (Photofrin®) mediated interstitial photodynamic therapy (I-PDT) shows promise for treating advanced head and neck cancer.

  • 2

    A Phase 1/2 clinical study (NCT03727061) is evaluating the safety and efficacy of I-PDT in patients with recurrent head and neck cancer.

  • 3

    The study targets patients who have not responded to standard therapy and are not candidates for curative treatment.

  • 4

    Gal Shafirstein, DSc, leads the research at Roswell Park, focusing on the potential of I-PDT in challenging cases.

  • 5

    The video provides background on I-PDT and details about the clinical study starting around the 9:00 minute mark.

Original Source(s)

Interstitial Photodynamic Therapy (PDT) for the Treatment of Patients with Locally Advanced or Recurrent Head and Neck Cancer

  • August 5, 2019

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