Cell Therapy Trial Targets Corneal Disease - Takeaways - MDSpire
Clinical Guidelines

Cell Therapy Trial Targets Corneal Disease

  • May 4, 2026

  • 2 min

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  • 1

    AURN001 is in a phase 3 ASTRA trial for corneal endothelial disease.

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    Focus on efficacy/safety and ≥15-letter improvement in BCVA.

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    12 U.S. trial sites.

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    Combines cultured endothelial cells and rho-kinase inhibitor.

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    Aims to reduce reliance on donor tissue.

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    Previous success in Japan; seeking U.S. biologics application.

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    Addresses global visual impairment due to endothelial dysfunction.

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