Guillain-Barré syndrome involving reproductive system revealed on 18F-FDG PET/CT: a case report - Takeaways - MDSpire

Guillain-Barré syndrome involving reproductive system revealed on 18F-FDG PET/CT: a case report

  • By

  • Huiling Li

  • Xinzhong Hao

  • Zhifang Wu

  • Sijin Li

  • Li Li

  • June 1, 2026

  • 0 min

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  • 1

    Guillain-Barré syndrome (GBS) is an immune-mediated acute inflammatory peripheral neuropathy with rare central and reproductive system involvement.

  • 2

    A 67-year-old man with GBS showed significant reproductive system involvement, identified via 18F-FDG PET/CT imaging.

  • 3

    The imaging revealed multifocal hypermetabolism in the nerve roots, cerebral cortex, hypothalamus, medulla oblongata, and right testis.

  • 4

    Histopathological examination confirmed orchitis with inflammatory infiltration, highlighting extraneural involvement in GBS.

  • 5

    This case demonstrates the utility of 18F-FDG PET/CT in assessing systemic disease and inflammatory activity in complex GBS presentations.

Original Source(s)

Guillain-Barré syndrome involving reproductive system revealed on 18F-FDG PET/CT: a case report

  • by Huiling Li, Xinzhong Hao, Zhifang Wu, Sijin Li, Li Li

  • June 1, 2026

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