Risk Factors for Bone Microarchitecture Impairments in Older Men With Type 2 Diabetes—The MrOS Study - Takeaways - MDSpire

Risk Factors for Bone Microarchitecture Impairments in Older Men With Type 2 Diabetes—The MrOS Study

  • By

  • Malak Faraj

  • Ann V Schwartz

  • Andrew J Burghardt

  • Dennis Black

  • Eric Orwoll

  • Elsa S Strotmeyer

  • Eric Vittinghoff

  • Marta Fogolari

  • Silvia Angeletti

  • Giuseppe Banfi

  • Giovanni Lombardi

  • Gina Woods

  • Li-Yung Lui

  • Mary Bouxsein

  • Nicola Napoli

  • July 12, 2024

  • 0 min

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  • 1

    Older men with type 2 diabetes mellitus (T2DM) exhibit smaller bone size compared to those without diabetes, potentially increasing skeletal fragility.

  • 2

    Diabetes duration of 10 years or more is linked to higher cortical porosity in men with T2DM, while insulin use correlates with lower cortical area and thickness.

  • 3

    High-resolution peripheral quantitative computed tomography (HR-pQCT) reveals significant differences in bone microarchitecture between T2DM and non-T2DM men.

  • 4

    Lower cortical area, thickness, and bone mineral density at distal sites are associated with an increased risk of nonvertebral fractures in T2DM.

  • 5

    The study highlights the need for effective interventions to prevent fractures in older men with T2DM due to their increased fracture risk.

Original Source(s)

Risk Factors for Bone Microarchitecture Impairments in Older Men With Type 2 Diabetes—The MrOS Study

  • by Malak Faraj, Ann V Schwartz, Andrew J Burghardt, Dennis Black, Eric Orwoll, Elsa S Strotmeyer, Eric Vittinghoff, Marta Fogolari, Silvia Angeletti, Giuseppe Banfi, Giovanni Lombardi, Gina Woods, Li-Yung Lui, Mary Bouxsein, Nicola Napoli

  • July 12, 2024

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