Tuber intake is independently associated with reduced risk of Hashimoto’s thyroiditis: a community-based cross-sectional study - Takeaways - MDSpire

Tuber intake is independently associated with reduced risk of Hashimoto’s thyroiditis: a community-based cross-sectional study

  • By

  • Xiaochen Ji

  • Guohua Hao

  • Bowei Su

  • Bing Wang

  • Zhengnan Gao

  • July 14, 2026

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  • 1

    Hashimoto’s thyroiditis (HT) is the leading cause of autoimmune hypothyroidism, with dietary factors implicated in its pathogenesis.

  • 2

    In a study of 7,878 adults, adequate tuber intake was associated with a lower likelihood of developing HT.

  • 3

    The prevalence of HT in the cohort was 29.3%, with female sex and elevated cholesterol identified as independent metabolic predictors.

  • 4

    Mendelian randomization indicated that folic acid supplementation causally increased HT risk, highlighting public health concerns.

  • 5

    The study suggests a U-shaped dose-response relationship for tuber intake, where both inadequate and excessive consumption may influence HT risk.

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