Recent advances in dissolving microneedles for breast cancer immunotherapy: local delivery and tumor microenvironment remodeling - Takeaways - MDSpire

Recent advances in dissolving microneedles for breast cancer immunotherapy: local delivery and tumor microenvironment remodeling

  • By

  • Yingcui Chen

  • Li Song

  • Yingze Zhu

  • Zhuoqi Zhang

  • Yige Lu

  • Xinyue Wang

  • Hui Pang

  • May 15, 2026

  • 0 min

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  • 1

    Breast cancer has low immunogenicity, limiting the effectiveness of immune checkpoint inhibitors in treatment.

  • 2

    Dissolving microneedles (DMNs) offer a minimally invasive method for targeted delivery of immunotherapy in breast cancer.

  • 3

    DMNs enhance immune activation by delivering antigens directly to antigen-presenting cells in the skin.

  • 4

    The use of DMNs can potentially remodel the immunosuppressive tumor microenvironment, improving therapy outcomes.

  • 5

    Recent studies show DMNs provide better immune activation and antitumor effects compared to traditional systemic administration.

Original Source(s)

Recent advances in dissolving microneedles for breast cancer immunotherapy: local delivery and tumor microenvironment remodeling

  • by Yingcui Chen, Li Song, Yingze Zhu, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Hui Pang

  • May 15, 2026

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