Construction and validation of a risk prediction model for early ventilator-induced diaphragm dysfunction in mechanically ventilated patients - Takeaways - MDSpire

Construction and validation of a risk prediction model for early ventilator-induced diaphragm dysfunction in mechanically ventilated patients

  • By

  • Min-Qing Long

  • Yu-Ting Liu

  • June 25, 2026

  • 0 min

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  • 1

    Mechanical ventilation can induce ventilator-induced diaphragm dysfunction (VIDD) within 24 hours, diagnosed via diaphragm ultrasound.

  • 2

    A study of 470 ICU patients identified five independent risk factors for early VIDD, including complicated sepsis and specific APACHE II scores.

  • 3

    The constructed nomogram model demonstrated an AUC of 0.820 in the modeling group, indicating strong predictive ability for early VIDD.

  • 4

    The model's calibration curve showed high agreement between predicted and actual values, confirming its clinical validity.

  • 5

    This nomogram can serve as a quantitative tool for early identification of high-risk patients in clinical practice.

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