Improving methodology of radiosurgery for posterior fossa cavernomas: higher volume, lower dose

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Cavernous malformations (CM) are low-flow vascular abnormalities in the central nervous system, prone to hemorrhage and often requiring intervention.
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Radiosurgery (RS) has emerged as a treatment option for CM, particularly in high-risk locations like the brainstem and posterior fossa.
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A prospective study involving 33 patients treated with CyberKnife radiosurgery showed promising results in reducing hemorrhage risk.
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The median marginal dose for radiosurgery was tailored based on CM volume, with doses ranging from 12 Gy to 18 Gy.
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Follow-up assessments indicated a significant reduction in hemorrhage rates post-radiosurgery, enhancing patient outcomes.

Acta Neurochirurgica

by François Nataf, Nathaniel Scher, Marc Bollet, Guillaume Mulier, Andrei Birladeanu, Lucian Sopanda, Jérôme Lambert, Gauthier Bouilhol, Stéphanie Guey, Homa Adle-Biassette, Anne-Laure Bernat, Rosaria Abbritti, Thibault Passeri, Emmanuel Mandonnet, Sébastien Froelich
February 1, 2025

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